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Clomiphene citrate (Serpafar) is not an anabolic androgenic steroid. Since it is a synthetic estrogen it belongs, however, to the group of sex hormones. In school medicine Clomiphene citrate® is normally used to trigger ovulation. Clomiphene citrate also has a strong influence on the hypothalamohypophysial testicular axis. It stimulates the hypophysis to release more gonadotropin so that a faster and higher release of FSH (follicle stimulating hormone) and LH (luteinizing hormone) occurs. This results in an elevated endogenous (body's own) testosterone level. Clomiphene citrate® is especially effective when the body's own testosterone production, due to the intake ofanabolic/androgenic steroids, is suppressed.

In most cases Serpafar can normalize the testosterone level and the spermatogenesis (sperm development) within 10- 14 days. For this reason Serpafar is primarily taken after steroids are discontinued. At this time it is extremely important to bring the testosterone production to a normal level as quickly as possible so that the loss of strength and muscle mass is minimized. Even better results can be achieved if Clomiphene citrate (Serpafar) is combined with HCG or when Clomiphene citrate® is used after the intake of HCG.

Paradoxically, although Clomiphene citrate is a synthetic estrogen it also works as an anti-estrogen. The reason is that Clomiphene citrate® has only a very low estrogenic effect and thus the stronger estrogens which, for example, form during the aromatization of steroids, are blocked at the receptors. These would include those that develop during the aromatizing of steroids. This does not prevent the steroids from aromatizing but the increased estrogen is mostly deactivated since it cannot at-tach to the receptors. The increased water retention and the possible signs of feminization can thus be reduced or even completely avoided. Since the antiestrogenic effect of Clomiphene citrate (Serpafar) is lower than those found in Proviron, Tamoxifen, and Testex it is mainly taken as a testosterone stimulant. Clomiphene citrate® is a medication that promotes the production of the body's own stimulating hormone, gonadotropin, which in turn increases the testosterone level. It is, for example, administered to women as a so-called anti-estrogen to trigger ovulation ("ovulation stimulator").

Side effects of Serpafar are very rare if reasonable dosages are taken. Possible side effects are climacteric hot flashes and occasional visual disturbances, which can manifest themselves in blurred vision, giving flickering or flashing. Should visual disturbances occur, the manufacturer recommends discontinuing Clomiphene citrate® treatment. Inadequate liver functions cannot be excluded; however, they are very unlikely. In women enlargement of the ovaries and abdominal pain can occur since Clomifen citrat® stimulates the ovaries. When taking Serpafar multiple pregnancies are possible as well. As for the dosage, 50-100 mg/day (1 -2 tablets) seems to be sufficient. The tablets are usually taken with fluids after meals. If several tablets are taken it is recommended that they be administered in equal doses distributed throughout the day. The duration of intake has been rumored to not be taken for longer than 10-14 days. This is incorrect. Clinical studies with male patients have shown Clomiphene citrate® to be used for up to a year or longer.

Most athletes begin with 25 - 100 mg/day, taking 25 - 50 mg every morning and evening after meals. After the 7 day the dosage is often reduced to only one 50 mg tablet per day. It is normally not necessary to take the compound for more than 10-20 days in order to increase the endogenous testosterone production.

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